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Neuropathy refers to a variety of diseases that affect the nervous system. The most common type of neuropathy is called peripheral neuropathy, which describes damage to the peripheral nervous system, the vast communications network that transmits information from the brain and spinal cord (the central nervous system) to every other part of the body. Symptoms of neuropathy are related to the type of affected nerve and may be seen over a period of days, weeks, or years. Muscle weakness is the most common symptom of motor nerve damage. Other symptoms may include painful cramps and uncontrolled muscle twitching visible under the skin, muscle loss, bone degeneration, and changes in the skin, hair, and nails. No medical treatments now exist that can cure inherited peripheral neuropathy. However, there are therapies for many other forms. Any underlying condition is treated first, followed by symptomatic treatment. Peripheral nerves have the ability to regenerate, as long as the nerve cell itself has not been killed. Symptoms often can be controlled, and eliminating the causes of specific forms of neuropathy often can prevent new damage. |
Neuropathy is one area in which we do a substantial amount of compounding for diabetes. Neuropathies are characterized by decreased nerve conduction and sensory function that creates a tremendous amount
pain. Peripheral neuropathies are a big contributing factor to the majority of amputations among diabetic patients. We compound a neuropathy gel using a Pluronic lecithin-organogel |
(PLO) base to be applied topically to the affected area three to four times a day. We vary this formula according to the intensity of the pain and the type of neuropathy. We counsel patients on how to apply these PLO gels and how often to apply them. We also request that they keep a daily journal of pain intensity, as well as symptomatic relief, so they can report back to us. Using this information, we can then make the appropriate adjustments.